Calcium exchange in vascular smooth muscle, action of noradrenaline and lanthanum.
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چکیده
منابع مشابه
Vascular Smooth Muscle Calcium Channels
Voltage-gated Ca 21 channels of the plasma membrane open in response to changes in cell membrane potential, providing an important pathway for regulated entry of extracellular Ca ions. Ca channels comprise a family of structurally related proteins displaying tissueand stage-specific expression. They are classified as either high voltage-activated (HVA) or low voltage-activated (LVA) and can be ...
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Hypertension is a progressive disease involving an increase in arterial constriction. It constitutes a major risk factor leading to stroke, heart disease, and kidney failure. Understanding the molecular pathways involved in arterial tone regulation is crucial to increasing our understanding of blood pressure regulation. Recently, a novel mechanism involving small-localized bursts of calcium ins...
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The possible involvement of a GTP-binding protein in the regulation of Ca2' channels by angiotensin II (Ang II) in vascular muscle cells was investigated by the whole-cell voltage-clamp method. Single cells were freshly isolated from guinea pig portal vein. The pipette solution contained high Cs4 to inhibit K4 currents and thereby isolate the Ca2+ channel current. Ba24 (2 mM) was in the bath so...
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ژورنال
عنوان ژورنال: The Journal of Physiology
سال: 1976
ISSN: 0022-3751
DOI: 10.1113/jphysiol.1976.sp011501